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Πλοήγηση ανά Θέμα "Hydrodynamic gene therapy"

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    • Minimal invasive technique for gene delivery in porcine liver lobe segment 

      Katsimpoulas, M.; Zacharoulis, D.; Rountas, C.; Dimitriou, C.; Mantziaras, G.; Kostomitsopoulos, N.; Habib, N.; Kostakis, A. (2011)
      Introduction: The feasibility and outcome of large volume injection of gene solution in a segment of a liver lobe, without backflow, were studied in a porcine model, using a custom-designed balloon catheter. Method: Eight ...

    • Minimally invasive and selective hydrodynamic gene therapy of liver segments in the pig and human 

      Khorsandi, S. E.; Bachellier, P.; Weber, J. C.; Greget, M.; Jaeck, D.; Zacharoulis, D.; Rountas, C.; Helmy, S.; Helmy, A.; Al-Waracky, M.; Salama, H.; Jiao, L.; Nicholls, J.; Davies, A. J.; Levicar, N.; Jensen, S.; Habib, N. (2008)
      This paper highlights our experience of the transfer of hydrodynamic gene therapy (HGT) from the large animal, the pig, into clinical practice. The modification of balloon catheters and the development of a minimally ...